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Chloride (Cl−)

BMP / Electrolytes
Normal range
98–106 mEq/L

SI: 98–106 mmol/L

Critical low: < 80 mEq/L · Critical high: > 115 mEq/L

☎ When to call

Rarely escalated alone — escalate the sodium, acid-base, or volume problem it travels with.

What you do
  • Usually moves with sodium — interpret them together
  • High Cl after lots of NS? Flag it — hyperchloremic acidosis is a real thing on rounds
Causes of HIGH chloride
DehydrationLarge-volume normal salineMetabolic acidosisRenal disease
Causes of LOW chloride
Vomiting, NG suctionDiureticsMetabolic alkalosis
Source: Pagana, Mosby's Manual of Diagnostic and Laboratory Tests, 7th ed.Reference only — verify against your facility's policy.

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