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AST

Liver
Normal range
10–40 U/L (values vary by lab)
☎ When to call

Transaminases in the thousands, or rising LFTs with confusion (hepatic encephalopathy) — call the provider.

What you do
  • AST > ALT ~2:1 suggests alcohol; ALT > AST suggests viral/NAFLD
  • Numbers in the thousands: think acetaminophen or ischemia — check the med history TODAY
Causes of HIGH ast
Hepatitis (viral, alcoholic, drug)Acetaminophen toxicityShock liver (ischemia)Muscle injury (it's not liver-specific)
Causes of LOW ast
Not clinically significant
Source: Pagana, Mosby's Manual of Diagnostic and Laboratory Tests, 7th ed.Reference only — verify against your facility's policy.

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