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Chloride (Cl⁻)

Normal 98–106 mEq/L
Why it matters

Sodium's shadow and the acid-base sidekick — moves with Na, inverse to bicarb.

LOW — Hypochloremia (< 98)
Causes
Vomiting, NG suction (losing HCl)DiureticsMetabolic alkalosis
Signs
Usually the signs of the alkalosis or the sodium problem it rides with
Nursing actions
  • Track NG output volumes — that's where the chloride went
  • Anticipate NS-based replacement
HIGH — Hyperchloremia (> 106)
Causes
Large-volume normal salineDehydrationMetabolic acidosis
Signs
Usually silent — shows in the acid-base picture
Nursing actions
  • Flag multi-liter NS days on rounds — hyperchloremic acidosis is a known consequence; balanced fluids may be preferred
Source: Ignatavicius, Medical-Surgical Nursing, 10th ed.Reference only — verify against your facility's policy.

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