DOACs (Direct Oral Anticoagulants)
-xaban, dabigatranHow it works
Directly block factor Xa (or thrombin) — predictable effect, no routine INR monitoring.
You'll see
Used for
Side effects
Monitor
- Renal function — most are renally cleared and renally dosed
- Missed-dose window matters: short half-life means protection fades fast
- Reversal: andexanet alfa (Xa inhibitors), idarucizumab (dabigatran)
🎓 Patient teaching
Do not skip doses — protection wears off within a day. Don't stop before procedures without instruction. Report falls (bleeding risk), dark stools.
Source: Lehne's Pharmacology for Nursing Care, 11th ed.Reference only — verify against your facility's policy.
