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Calcium Channel Blockers

-dipine (plus diltiazem, verapamil)
How it works

Block calcium entry into vascular and cardiac muscle → vessels relax; diltiazem/verapamil also slow the heart's conduction.

You'll see
amlodipinenifedipinediltiazemverapamil
Used for
HypertensionAnginaA-fib rate control (diltiazem/verapamil)
Side effects
Peripheral edema (dipines)Bradycardia, hypotension (diltiazem/verapamil)Constipation (verapamil)Headache, flushing
Monitor
  • HR and BP before dose — verapamil/diltiazem + beta blocker together compounds bradycardia
  • New ankle swelling on a dipine is the drug, not always heart failure — assess before diuresing
🎓 Patient teaching

Avoid grapefruit juice (raises levels). Report swelling, dizziness. Don't crush extended-release forms.

Source: Lehne's Pharmacology for Nursing Care, 11th ed.Reference only — verify against your facility's policy.

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